What are the 5 Types of Hyaluronic Acid Fillers?

What are the 5 Types of Hyaluronic Acid Fillers
Hi there, lover of renewal! Are you prepared to explore the world of hyaluronic acid fillers and learn about their revolutionary potential? Hyaluronic acid fillers may be the solution for you if you want to improve your features or get a more youthful, radiant appearance.

However, picking the best brand might be overwhelming because many are available, including Juvederm, Restylane, Belotero, Revanesse, and the RHA Collection.

Don’t worry, though! This guide explores the unique qualities and appropriate uses of each brand. We’ll solve the puzzles surrounding injectable hyaluronic acid fillers and examine the five varieties that can assist you in reaching your desired cosmetic outcomes.

So, let’s set out on this adventure and discover the wonders and types of hyaluronic acid fillers together!

Types of Fillers

Several kinds of fillers are available, each intended to solve a particular issue and accomplish a specific aesthetic objective. Let’s examine a few of the most prevalent kinds:

Hyaluronic Acid Fillers

Although many different fillers exist, the most popular ones are based on hyaluronic acid (HA). Your body naturally produces HA, a sugar molecule essential for maintaining the hydration and plumpness of your skin. Our bodies create less HA as we age, which causes wrinkles and drooping skin. HA fillers restore lost HA, providing a natural-looking means of achieving a younger look.

The effects are transient, lasting at least six to twelve months until the body progressively and naturally absorbs the particles. To help reduce discomfort before and after treatment, the doctor injects lidocaine into the majority of HA fillers. HA fillers with FDA approval include:

  • Products made by Juvéderm: Juvéderm XC, VOLUMA, VOLBELLA, and VOLLURE
  • Restylane products include Restylane, silk, Lyft, refyne, Defyne, Kysse, and contour.
  • Belotero Equilibrium
  • Revanesse
  • Compilation of RHA: RHA 2, RHA 3, and RHA 4.

But in addition to HA, there are other filler choices as well:

Calcium Hydroxylapatite

Calcium hydroxylapatite (CaHA) can increase bone volume and stimulate collagen formation.

When used as a filler, the smooth gel in which the calcium particles are suspended contains about tiny amounts. Generally speaking, a CaHA filler lasts longer—roughly a year for most patients—and has a thicker consistency than a hyaluronic acid filler.

Doctors use Calcium hydroxylapatite for deeper wrinkles, lines, and regions requiring structural support. Also, it stimulates the creation of natural collagen. Radiesse® is one CaHA filler that the FDA has approved.

Polylactic Acid (PLLA)

Polylactic acid is a synthetic material that degrades naturally and is safe for usage in the body. Dissolvable stitches are among the medical devices that have been using it for a long time.

Although the filler gel disappears a few days after treatment, products containing poly-L-lactic acid are technically categorized as “collagen stimulators” because their primary method of smoothing fine wrinkles is by assisting your skin in regenerating its collagen.

Although they take longer to manifest their effects fully, PLLA fillers provide longer-lasting results than HA fillers. Doctors usually use Polylactic fillers for facial wrinkles, and the effects often endure for more than two years. Polylactic acid fillers approved by the FDA include Sculptra® Aesthetic.

Polymethylmethacrylate (PMMA)

Polymethylmethacrylate, or PMMA, is a particular kind of plastic microsphere suspended in a collagen solution. Because of its permanent nature and potential for difficulties, it is the least prevalent type of filler.

Polymethylmethacrylate, or PMMA, has been a synthetic, biocompatible medical material for the last century. Doctors use PMMA in dermal fillers as a “microsphere,” or tiny ball, that stays under the skin permanently to give support.

One naturally occurring substance in the skin, collagen, gives it structure and rigidity. PMMA fillers will also contain this substance. Among the PMMA fillers that have FDA approval is Bellafill® (formerly known as Artefill).

Autologous Fat Transfer

Autologous fat injections are the only injectable filler therapy that requires surgery; however, the results can last for years. The practitioner takes your fat out of another area of your body, typically by liposuction (autologous meaning “from the same person”).

The fat is washed and injected into the face to help add volume to the lower eyelids, cheeks, temples, and other areas. Only skilled, board-certified cosmetic surgeons should perform fat injections, as they are specialists who guarantee both safety and outstanding results.

Now, we get back to our focus of the day, injectable hyaluronic acid fillers; what are they, and what types exist? Keep going; we are about to find out!

What Are Hyaluronic Acid Fillers?

Practitioners use injectable hyaluronic acid (HA) fillers using a cannula needle as a cosmetic treatment to smooth wrinkles, add volume, and improve facial characteristics. Because HA is a chemical that occurs naturally in the body and because HA fillers provide a minimally intrusive means of looking younger, they are trendy.

The following describes HA fillers and their mechanism of action:

  • Your body has the sugar molecule hyaluronic acid (HA), mainly concentrated in the joints, skin, and eyes. By drawing and retaining water molecules, HA is a sponge that keeps your skin hydrated and plump.
  • Aging and HA Depletion: As you age, your body naturally makes less HA. Reduced HA levels contribute to sagging, dry, and wrinkled skin.

But not every HA filler is made equally. HA fillers come in various forms with unique qualities intended to address specific issues and regions. The five primary kinds of HA fillers are broken down as follows:

What Are Hyaluronic Acid Fillers
5 Types of Hyaluronic Acid Fillers

Let’s examine five well-known hyaluronic acid (HA) filler brands, their salient characteristics, applications, and benefits. Each brand customizes the HA concentration, particle size, and cross-linking technique to provide unique outcomes.

1. Juvéderm: The Versatile Volumizer
Juvéderm The Versatile Volumizer

Among the most popular brands of facial fillers is Juvederm, produced by Allergan. It provides various products, including Juvederm Ultra, Juvederm Ultra Plus, Juvederm Voluma, and Juvederm Volbella, suited to multiple demands.

Hyaluronic acid is added to each product in different amounts to address concerns like cheek enlargement, lip augmentation, and the smoothing of moderate to severe facial wrinkles and folds.

  • Juvéderm XC is the perfect solution for treating moderate to severe face creases and folds, with lidocaine added for comfort.
  • VOLUMA’s thicker consistency volumizes the cheeks and midface area for up to two years. VOLBELLA’s silky gel solution produces natural lip augmentation and perioral line repair results.
  • VOLLURE preserves facial flexibility by providing long-lasting wrinkles and fold treatments for up to 18 months.

2. Restylane: The Subtlety Master

Galderma’s Restylane is another famous brand of hyaluronic acid filler. It contains items such as Restylane Silk, Restylane Defyne, Restylane Lyft, and Restylane Refyne. These fillers target various parts of the face, including the lips, cheeks, marionette lines, and nasolabial folds, to produce long-lasting, natural-looking results.

The primary goals of Restylane Silk are to smooth perioral lines and subtly enhance lips. Lyft tackles the loss of cheek volume and provides a lifted appearance lasting up to two years. While addressing moderate to severe facial creases and folds, Refyne and Defyne allow for natural expression.

While Contour uses a firm gel formulation to sculpt facial features, Kysse amplifies lip volume and definition for up to a year.

3. Belotero: The Expert in Fine Lines

Merz Pharmaceuticals’ Belotero brand provides a selection of hyaluronic acid fillers designed to blend in with the skin for understated and natural-looking results. Belotero products, including Belotero Balance, Belotero Soft, Belotero Intense, and Belotero Volume, can treat various face areas, including fine lines, moderate to severe wrinkles, and facial contouring.

Correcting medium to severe facial wrinkles and folds, such as nasolabial folds and vertical lip lines, Belotero Balance blends easily into the skin. Its unique formula guarantees natural results without the chance of lumpiness or visibility, and the benefits last between six months and a year.

4. Revanesse: The Prospective Newcomer

Prollenium Medical Technologies’ brand of hyaluronic acid filler, Revanesse, is renowned for its smooth gel consistency and appearance of natural results. Practitioners use Thixofix cross-linking technology to formulate Revanesse fillers, such as Revanesse Versa and Revanesse Lips+, to provide the best possible tissue integration and durability. These fillers work well for plumping lips, improving facial contours, and reducing wrinkles.

This product provides a pleasant, minimally bruising and edema treatment for moderate to severe facial creases and folds. Its sophisticated recipe produces consistent, smooth effects lasting up to a year.

5. The RHA Collection: Designed for Movement

Developed by TEOXANE Laboratories, The RHA Collection offers dynamic HA fillers that adjust to the face’s natural expression. Compared to conventional fillers, RHA, or Resilient Hyaluronic Acid, RHA is known for its distinctive formulation, which resembles the natural hyaluronic acid in the skin and produces a more flexible and dynamic effect.

Fillers from the RHA Collection preserve a natural expression by adjusting to face movements.

Based on the product, long-lasting effects might last anywhere from 12 to 24 months.

RHA fillers are designed to adjust to facial expressions and dynamic motions. Because they include more potent hyaluronic acid molecules, they can flex and contract in response to facial expressions like frowning or smiling. By preventing rigidity or forced facial expressions, this dynamic aspect aids in preserving a natural feel and appearance.

The RHA range comprises multiple formulations to address distinct facial areas and treatment requirements. These comprise RHAs 2, 3, and 4, each with unique viscoelastic characteristics that make them suitable for treating moderate to severe folds and facial wrinkles. Teoxane also provides customized RHA fillers for sensitive regions like lips and hollows around the eyes.

What are the Risks Associated with Each Type of Filler

What are the Risks Associated with Each Type of Filler?

Below is a summary of the possible dangers connected to each kind of filler brand:


Common side effects that may occur at the injection site include redness, swelling, bruising, itching, and discomfort. What else?

  • Allergic Reactions: Although uncommon, allergic reactions to Juvederm fillers can happen and cause swelling, hives, rash, or itching.
  • Infection: When practitioners use appropriate sterile procedures, there is a chance of infection at the injection site, but it is minimal.
  • Granulomas or Nodules: In rare cases, lumps or nodules may develop at the injection site, requiring additional care.
  • Vascular Complications: If filler material accidentally penetrates blood vessels during injection, as is the case with all fillers, there may be a risk of vascular complications.


Like Juvederm, there are dangers associated with Restylane fillers, including infection, allergic reactions, nodules or granulomas, and vascular problems.


  • Reactions at the Injection Site: Bruising, redness, swelling, and soreness are common but typically transient.
  • Allergy Reactions: Although they are uncommon, allergies can happen.
  • Infection: At the injection site, there is a chance of infection.
  • Nodules or Granulomas: Although uncommon, nodule or granuloma formation is possible.
  • Vascular issues: If filler material gets into blood arteries after injection, similar to other fillers, vascular issues could occur.

Teoxane (RHA Collection)

Injection site responses, allergic reactions, infection, nodules or granulomas, and vascular problems are among the dangers of RHA collection, just like with other hyaluronic acid fillers.

Because of their increased elasticity and dynamic nature, RHA fillers may be less likely to exhibit obvious lumpiness or migration than other fillers.


Risks associated with Revanesse fillers include vascular problems, nodules or granulomas, allergic responses, injection site reactions, and infection.

Thanks to its Thixofix cross-linking technology, Revanesse promises to reduce the chance of migration or lumpiness and give a smooth gel consistency.

Generally, most patients get satisfactory results when trained healthcare experts appropriately administer dermal filler treatments. However, these hazards are always a possibility with any treatment. Before receiving filler treatments, people should thoroughly discuss these risks with their healthcare professional and report any relevant medical history or allergies.

Selecting the Appropriate HA Filler

There isn’t a single, universally applicable option for HA fillers. Which option is ideal for you will depend on your particular problems.

  • Treatment Area: Doctors intend to use certain fillers in particular treatment areas. Think about the areas you wish to improve, such as lips, wrinkles, or volume.
  • Goal: Are you going for a big volumization or a subtle correction? Talk about your objectives with your cosmetic surgeon or dermatologist.
  • Filler Properties: Fillers differ in composition and thickness. Your physician will suggest a filler that works well with your tissues and produces the desired outcome.


A safe and efficient method of achieving a rejuvenated, young appearance is with HA fillers. By comprehending the science underlying HA and the distinct qualities of various brands, you will be equipped to engage in your session actively.

Remember that communication is essential. Talk to your doctor about the results you hope to achieve, and don’t be shy about sharing your preferences. If you have the correct information and a trained specialist, you may embrace your most self-assured self and realize the transformational potential of using the appropriate HA fillers.

Utilize Diaminy Hyaluronic Acid Fillers to Enhance Your Beauty

Discover the key to glowing, youthful skin with superior hyaluronic acid fillers from Diaminy. Diaminy offers a variety of fillers made with the best ingredients and state-of-the-art technologies intended to improve and renew your natural attractiveness.

Diaminy is ideal for shaping facial features, plumping lips, or smoothing wrinkles. Upgrade your beauty routine and discover the revolutionary potential of Diaminy hyaluronic acid fillers. Shop online today to start your path toward glowing skin!

Utilize Diaminy Hyaluronic Acid Fillers to Enhance Your Beauty

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